Scientific Consulting
With over 17 years of analytical chemistry experience, I can help your laboratory prepare for chromatography and mass spectrometry technologies.
HPLC
Technologies
I can support High Performance Liquid Chromatography (HPLC) including training. This includes all detector types (UV-VIS, Photodiode array, Fluorescence, Refractive Index, Evaporative Light Scattering Detector) and modules including fraction collectors. With over 10 years of experience with LC systems, I am the right candidate to train your personnel.
LCMS
Nichols Consulting LLC can providing comprehensive laboratory preparedness services for molecular assays involving liquid chromatography mass spectrometry (LCMS). I have 18 years of experience using mass spectrometry. I have used most varieties of mass analyzers including quadrupoles, triple quadrupoles, time-of-flight, and ion traps. Not only am I experienced for method development and training, but I can advise which is the correct mass analyzer for your application.
Technician Training
I have taught scores of technicians and researchers how to use chromatography and mass spectrometry equipment. Proper training starts at sample preparation and goes through data analysis.
Method Design
What are you measuring? Let's review the literature together so we can determine the best methods for your practice. I have a diverse background in sample preparation, and I can help you develop a process that works for your target analyte.
Services
Technical Consulting
Are you interested in bringing testing in-house? Are you unsure of the requirements of starting a lab? Do you want to have someone look at your business plan to make sure you aren't missing anything?
Starting a lab comes with many challenges. You want to make sure that you have accounted for all the financial costs of doing business. I can also help you to pick out the best hardware for your specific task. Purchasing the incorrect hardware can be very costly.
Validation Support
Does your lab require ISO 17025 or ISO 9001 certification, but you don't know where to start? Are you having challenges passing proficiency testing?
If your plan to implement third party testing, or if you want to bring regulated testing in-house for your product, local ordinances will likely require certification. This will differ depending on the industry and governing body. This usually involves proficiency or validation studies be submitted.
Nichols Consulting can support your lab directors, managers, scientists, and technicians to complete method validation and accreditation.
Customer Success Management
Are you a vendor of analytical equipment? Do you need a technical expert to support your customers? I have a strong technical background, a proven track record of effective communication, and industry experience supporting customers.
Ion Mobility and Drift Cells
Ion Mobility provides a powerful separation that is orthogonal to both chromatographic and mass analysis. The technique has historically been reserved for R&D laboratories, but with new commercial products emerging each year these techniques are finding their place in more laboratories across the world. An exciting technology, I would love to discuss how ion mobility spectrometry can help your measurements.
Allied Analytical Techniques
Interested in other allied topics, but don't know where to begin. I can investigate your application to suggest the correct technology such as Gas Chromatography (GC), Inductively coupled Plasma (ICP), Fourier Transform Infrared Spectroscopy (FTIR), and Thermal Gravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Dynamic Vapor Sorption (DVS), X-ray fluorescence (XRF), or scanning electron microscopy (SEM).
Laboratory Design
Laboratory design is an important element of being successful with analytical measurements. Let's visit your space and discuss what elements you will require to be successful at implementing the technology. I can help design floor plans and work with contractors to install important elements such as electricity, air conditioning, ventilation, and waste management.